Chronic psychosocial stressors in adulthood: Studies in mice, rats and tree shrews
نویسندگان
چکیده
منابع مشابه
Chronic psychosocial stressors in adulthood: Studies in mice, rats and tree shrews
Human psychological stress is the major environmental risk factor for major depression and certain of the anxiety disorders. Psychological stressors often occur in the context of the adult social environment, and they or the memory formed of them impact on the individual across an extended period, thereby constituting chronic psychosocial stress (CPS). Psychosocial stressors often involve loss ...
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We have shown previously that repeated laboratory restraint stress or daily corticosterone administration affects the structure of CA3 hippocampal neurons in rats. In the present study, we investigated the effect of repeated daily psychosocial stress on the structure of hippocampal CA3 pyramidal neurons in male tree shrews (Tupaia belangeri). Male tree shrews develop social hierarchies in which...
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To improve our knowledge of the causal mechanisms of stress-related disorders such as depression, we need animal models that mirror the situation in patients. One promising model is the chronic psychosocial stress paradigm in male tree shrews, which is based on the territorial behaviour of these animals that can be used to establish naturally occurring challenging situations under experimental ...
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ژورنال
عنوان ژورنال: Neurobiology of Stress
سال: 2017
ISSN: 2352-2895
DOI: 10.1016/j.ynstr.2016.10.001